As I write this, I have just returned from Pennsylvania. The news is spectacular and it is all good! On Wednesday evening, the Trust sat down for our annual meeting. Shortly after we began, Wayne Kompare, head of the Westie Foundation called. On speaker, he told the Trust that he is in negotiation with Virginia- Maryland Regional College of Veterinary Medicine to effect collaboration between them and Dr. Patrick Venta for testing of our CMO samples in an effort to identify the gene responsible for this problem. As many of you know, we have been working on this problem for many years without success, and it is hopeful that progress may be on the horizon. One of the issues to be resolved is whether the cheek swabs we have are capable of providing sufficient genetic material to be tested on the newer equipment available at Virginia-Maryland. Should this prove to be the case, this may be the answer to getting this project back on track.
On that evening we also learned of the reappointment of Lisa Kincheloe and John Leith for three year terms on the Trust. Both of these fine people do irreplaceable work for you and we are thankful that the Board has returned them to us.
On Friday evening, the Trust was privileged to present an educational presentation by Dr. Elaine Ostrander on the research she is doing for us attempting to identify the gene responsible for transitional cell carcinoma of the bladder (TCC). The Trust is indebted to Door County Scottie Rally, Inc., whose unfailing encouragement and financial support made the presentation possible.
What Dr. Ostrander told us is incredible. Just a year and a half into her research, they believe they have identified the gene responsible for TCC in the Scottish Terrier! Work remains to be done. There is an urgent, priority need for samples from Scotties twelve years of age or older who are free of cancer of any type. These samples will be used to eliminate those genes close to the suspect gene, in order to be able to say with absolute certainty that they are correct in their identification of the TCC gene.
When that occurs, and hopefully with a year, we will go to the marketplace and create an easily performed test for this despicable killer. Our next job will be to come to you and help you to understand the meaning of the test and your role in the long job of reducing and eventually eliminating this epidemic that takes over ten percent of our dogs. Think of what it will mean- the elimination of so much suffering, and a longer, healthier future for our dogs. So many taken prematurely in years past will not suffer this fate. It remains possible that within a decade, together we may extend the life expectancy of this breed by ten percent.
She also shared with us that their laboratory has determined that our gene is responsible for an entirely different cancer in an entirely unrelated breed. There is extreme interest and excitement around the world in the molecular genetics community that this single gene may prove to be responsible for many different cancers in many different breeds.
We have also learned recently that good progress is being made in the search for the gene responsible for cerebellar abiotrophy (CA) in the Scottish Terrier. It is my hope that soon we will be able to report the identification of this gene in our breed so that we can begin the work of reducing it’s prevalence in the population and prevent the production of affected dogs entirely. As many know, the gene has been identified recently in the American Staffordshire Terrier and in the Parson Russell Terrier and it is a matter of time before we accomplish this for our breed.
Samples, samples, samples! All the Trust can talk about is samples! Lovers of the Scottish Terrier have been incredibly generous for many years to the Health Trust. As Dr. John Leith and I drove Dr. Ostrander to the talk, she told me that what she needs at this time is samples from healthy twelve year old or older dogs. I urged her to just ask during her presentation, because I knew that people would respond. The future of this breed hangs on samples both today and far into the distant future. If you know of or own a dog whose sample can help our researchers, it is urgent that we include these dogs in the studies we have underway, and in the studies we will do in the future. Timing is critical in both the CA and the TCC effort. You have always come through for your dogs and we know you will do what is required to help, and we thank you.
On Friday the Trust offered the registry initiatives that we have offered for the past several years. We had a good response to this effort and were able to sign a number of dogs for reduced cost vWD testing, DNA profiling, and free patellar examinations. We thank the many people who have used these services and who have led the community in the registration of their dogs with CHIC. Your effort and example is proof of your commitment to a healthier future for our breed. I want to also thank Dr. Marcia Dawson, who performed the patellar examinations for us that day. As most of you know, Marcia has been a steadfast advocate for health and for the Health Trust for many years and we are grateful to her. Trustee Helen Prince knows the registry process cold, and should you have any questions in this area, Helen can guide you to the correct place.
Many of you attended the banquet on Friday evening. Helen Prince and I enjoyed the unique honor and extreme pleasure of presenting the Antonella Visconte di Madrone Health Advocate Award to Miss Gail Gaines. This award was last presented in 2002. Everyone knows Gail. She has bred sound, beautiful dogs for over forty years. She has also been a constant and abiding advocate for health in our breed. She has been a guiding force for the Trust since its inception, and many know that she has also guided and administered ScottiePhile over the years since its creation. Since the award cannot be offered to a sitting Trustee, many worried that we might never have an opportunity to present it. Gail’s recent retirement from the Trust afforded that opportunity. We are inspired by her example and wish her many, many years of happiness.
Louis A. Mitchell, M.D.
Chair, STCA Health Trust Fund
Bagpiper 2008 #3 Health Trust Newsletter
Health Trust Happenings
As you read this, MontgomeryCounty is again nearly upon us. The Trust has been busy putting together a program with something for everyone. On October 2, Thursday evening at six, make your plans to attend the Trust lecture by Elaine Ostrander, PhD. Elaine is Chair of the Cancer Genome Section, National Institutes of Health in Bethesda, Maryland and one of the world’s most respected researchers in the area of genetics and cancer. She will talk to us on the status of the research effort to discover the gene or genes responsible for transitional cell carcinoma (TCC) of the bladder in the Scottish and West Highland White Terriers. By this point in time, she will be late in the grant cycle funded by the Trust aimed at discovery of this gene and how to go about reducing the incidence of this problem.
Following our presentation, STCA will have a symposium for regional breed clubs. Everyone is encouraged to attend this presentation following immediately.
Then, on Friday, at LuLuTemple, the Trust will be on hand to provide you and your dogs with the testing we have been doing for several years. Reduced cost DNA profiling kits, vWD test kits, low-cost microchipping, and free testing for patellar luxation by our veterinarian Dr. Pam Hendrickson will all be available on that day. There has been a wonderful response over the years to this testing effort aimed at entering dogs into the open registry, and the Trust invites you to utilize these services. Mrs. Helen Prince knows the registry process inside and out and would be most pleased to answer any questions you may have. Please come and share with a Trustee your concerns and ideas on how the Trust can help your dogs going forward.
In recent months, we have received a spate of progress reports on research currently underway or completed by the Trust. We want to always keep you in the loop in terms of what your contributions have accomplished. I will briefly summarize where these projects are, and we would welcome the opportunity to discuss any of these in greater depth than is possible here.
Grant 395-A Elevated Serum Alkaline Phosphatase Activity in Scottish Terriers
This grant is finished. Dr. Zimmerman found that there appear to be abnormal and different adrenal hormones present in dogs with elevated alkaline phosphatase levels, not seen in dogs with normal levels of serum alkaline phosphatase. This correlated with more severe degenerative changes of the liver in the elevated alkaline phosphatase dogs. The Health Trust is contemplating a survey of the membership to allow members to report liver enzyme levels in their dogs, which could be used to construct a better graph of what levels appear to be “normal” at various ages. Elevated liver enzymes appear to be a very common problem in the Scottish Terrier.
Grant 407 The Genetics of Canine Cerebellar Degeneration (CA)
This was the first study funded in part by the Health Trust attempting to find the gene responsible for CA in four breeds. At the beginning of this study there was no DNA available in the Scottie and as a consequence the breeds screened were the Old English Sheepdog and the American Staffordshire Terrier. The time interval of this grant allowed the collection of numerous samples in affected Scotties and their relatives, which made possible the grant # 927 described below. The outcome of the present grant in the affected breeds was that they did find possible causative genes but have not determined the specific gene responsible.
Grant 593A Mapping Genes Associated with Canine Hemangiosarcoma
Dr. Kirsten Lindblad-Toh is searching for the gene responsible for this cancer in golden retrievers and additional breeds. Her laboratory has identified seven locations that appear to possibly be the cause, and they are now fine-mapping these areas for mutations. Should they succeed in determining the mutation, the Trust may pursue study of our breed at a future date- this work would obviously be greatly speeded by the present project.
Grant 615A-T Heritable Genetic Lesions in Canine Lymphoma
Dr. Modiano is working to determine the specific gene abnormalities responsible for lymphoma in a variety of breeds. It is predicted that this will allow them to determine heritable factors which influence the anomalies present in dogs with this cancer and also to predict the biological behavior of the cancer.
Grant 632 MicroRNAs and Canine Lymphoma
Dr. Kisseberth believes that testing equipment specifically designed to detect the abnormalities present in this cancer will allow him to classify the cancer and its behavior based on the abnormalities present. If successful this custom apparatus would allow rapid prediction of prognosis and therapeutic avenues. In other words, one can run the test and gain information which will allow us to determine prognosis and also guide us to the best treatments for our dogs.
Grant 754A Mapping of the Gene for TCC in the Scottish and West Highland WhiteTerrier
Dr. Ostrander is searching for the gene responsible for TCC in our breed. This grant has been underway for a year and additional samples are always needed. The samples on hand have been screened and they are now in the process of determining mutations present in affected dogs that are not present in unaffected dogs. We must patiently await her determination of the responsible gene before we move to develop a clinical test for dogs at risk for this disease. The Scottish Terrier is at twenty times greater risk for this cancer than mixed breed dogs.
Grant 768 Collaborative Study to Enhance Detection, Diagnosis and Treatment of Canine Lymphoma
This grant aims to improve the microscopic diagnosis of lymphoma by veterinary pathologists by testing their diagnostic skills using standardized sets of testing materials. The Health Trust made a small contribution to this grant along with many other breed clubs and the Canine Health Foundation.
Grant 896-A Phase One Trial for use of a single drug placed into the bladder for treatment of bladder cancer
Dr. Knapp has concluded this study, although they continue to observe four dogs treated. While Mitomycin C appears to be very effective in arresting the growth of the cancer, there were significant problems in a small percentage of dogs which led them to stop the study. She intends to provide a report for publication at a future date to explain the results and implications for future use of this therapy in the Scottish Terrier. While not a cure, it is possible that this treatment may offer palliation and extension of life in dogs affected with this disease.
Grant 927 Gene Discovery in Hereditary Cerebellar Abiotrophy of Scottish Terriers
This grant is in progress at this time. It is a stand-alone grant for Scottish Terriers and, as always, results will be enhanced by additional samples from affected dogs and their families. We need to patiently await word that Dr. Olby has determined the responsible gene before we move to the next stage, which will be the production of a commercial assay to determine susceptible dogs.
Samples, samples, samples. This is the grist which allows hope for a better day for our dogs. The Health Trust is working with CHIC to establish a sample collection which will be used by researchers hoping to solve numerous questions regarding problems which plague our dogs. The beauty of this is that it will someday allow us to NOT come to you for samples from your dogs every time we undertake a project. Presently we have not accomplished this goal, but you can help by presenting your dog for painless collection of cheek swabs or blood at some national specialties and major shows. We are in this together. The fancy has been most generous in donations of money and tissue over many years. The Trust is so thankful for this generosity.
Bagpiper 2008 #2 Health Trust Newsletter
Do We Need A Health Trust?
This was the question that the leadership and membership of the STCA considered as far back as fifteen years ago. There was a belief that our dogs lived less vigorous, healthy, long lives than might be the case should the club organize an arm whose simple goal was to enhance health and well-being of our dogs. There was no money to facilitate research into the diseases that plagued the dogs, nor was there an AKC Canine Health Foundation at the time. There were no registry initiatives that we now take for granted, nor were there funds for educational activities we now enjoy. So the leaders of the day forged ahead with the creation of the Trust. The vision of those leaders allowed the creation of the Trust, and now, it is healthy to examine what all the bake sales, raffles, and donations of time and money from so very many has grown into. Understand, as you read this,that it is written from a perspective of awe and appreciation for their vision. Because what we have been given has indeed enhanced the goals which led to creation of the Trust and gives great hope and promise for a brighter day for our dogs.
I know that there are those who would abolish the Trust. They say that we do not accomplish anything. They do not participate in our efforts or activities, nor do they help us with ideas or money. They believe the effort is wasted. It has been said to me that: “You cannot cure cancer.” While we all know that this is not strictly true, cancer remains the single most devastating category of disease in our breed. Taking the lives of more than fifty percent of purebred dogs, a single cancer, transitional cell carcinoma of the bladder, takes the lives of greater than one in ten Scottish Terriers! A great deal of our focus concerns this single class of disease, since it afflicts so many and so ravages the dogs and their owners.
To the notion that one cannot cure cancer, my response would be that the solution to cancer might lie beneath a grain of sand on a beach. The Trust has sponsored many, many grants aimed at obtaining information on one or another cancer. Many of the breed club health arms sponsor similar research on cancers prevalent in their breeds. The information from these projects is like turning over grains of sand in search of the answers we seek. It is often unclear at the time what the information means, but often the data gained in one project can be networked with insights gained in other studies to gain meaningful information that makes real progress in the treatment of a given disease.
This is not to say that we have a cure for many of the dreadful afflictions our dogs suffer today. However, as I write this, the Trust has ongoing research looking for the genetic defect operative in TCC. We have one of the most gifted researchers of our generation, Dr. Elaine Ostrander, head of the genetic oncology branch of the National Institutes of Health, working on this problem for us. I dare hope that she will tell us in the near future that she has found the responsible gene or genes causing this odious problem. And on that day it ceases to be rocket science to determine which dogs carry the gene. And on that day, we will have the power to do something about this epidemic. And so, while we are at present usually unable to cure TCC, there will come a day when we will have the power to decrease the number of dogs who will suffer this fate. Consider for a moment what normalizing the incidence of this disease- now twenty times as prevalent in our breed as in mixed-breed dogs, would do in terms of the average lifespan of the Scottie. Mind you, the goal is not the elimination of the disease, but rather, to reduce the disease to the level experienced by other breeds. I believe it will happen.
And, in the meantime while we await the answer to this problem, we are also funding research at Purdue with Dr. Debby Knapp, refining treatment protocols for presently affected dogs, which promises to offer longer remissions and less suffering than the dogs have experienced in the past. A cure? No. Progress? Yes. Because the most acceptable cancer is the one that did not happen at all.
The problem of cerebellar abiotrophy appeared explosively in the breed less than a decade ago. Helpless to change the fate of the affected dog, the Trust has recently funded the second research endeavor, partnering with the AKC Canine Health Foundation to allow Dr. Natasha Olby to search for the gene responsible for this miserable problem. Big money, high hopes and expectations expended to solve this problem. Absent the Trust, who could have paid the $40,000.00+ committed to date for this problem. Not to mention the many, many owners organized to contribute the DNA without which this research would be impossible. Will we solve this problem? I strongly believe we will, given time and resolve. Again, not the cure, but rather the solution to a terrible problem lies in our failure to produce the affected dog.
The Trust is aware that there are many problems urgently in need of solutions. We continuously search for quality research proposals in areas of concern to the breed. When we find these proposals, we examine them rigorously and fund those which pass muster. Some five years ago we were given a generous gift for research or education in the area of liver shunt. It has taken this period of time, but we now have the proposal, and will soon put this money to work, in partnership with several other breed clubs, in a search for the genetic defect operative in this problem.
It is appropriate here to mention the many other activities organized by the Trust. We regularly offer educational programs to enhance the spread of knowledge within the fancy, and aimed at offering information to help breeders and owners with problems they face. Registry initiatives facilitate easier dissemination of information useful to breeders. Low cost and subsidized testing offered by the Trust at national specialties helps owners better manage information on dogs they own and those they are considering breeding to. A newsletter sent to the regional clubs facilitates dissemination of information on the activities of the Trust, and provides articles of interest to owners.
You know, the moral imperative for the Trust is not only the dogs owned by the membership of the STCA. At the end of the day, the Trust works on behalf of every Scottish Terrier, including the 95% of dogs owned by people who do not belong to the STCA. The networking of knowledge mentioned earlier means that the Trust also works for all dogs of whatever breed, and that the work done by their breed arms also works for us. The Trust has a periodic dialog with the heads of the Cairn and Westie Foundation seeking common interests and brainstorming for advantage in the work we do for the dogs.
And so we return to the question of whether we need a Health Trust? Could any of us accomplish alone what the Trust has done over the past decade? Possibly, but the likelihood is small. Your Health Trust is one of only a half-dozen breed club health arms which has funded in excess of $100,000.00 in research projects with the AKC Canine Health Foundation. You have much to be proud of. And so I believe the answer is that together we have accomplished much that would never have occurred in the absence of a Trust.
I often ponder the position of the federal government that we should not work on or fund human stem cell research. The human imagination is such that, if we do not do it, it is a certainty that someone else will. You cannot stop progress in the acquisition of knowledge, because of the potential for networking that knowledge for the relief of suffering. The sequencing of the human and canine genome has meant that progress will come faster and at less cost in time and money. The Trust is populated by extremely gifted, well-intentioned people whose only goal is to offer you a healthier companion animal. Extraordinary time and effort is focused on this single goal. Do we need a Health Trust? Consider the alternative.
Louis A. Mitchell, M.D.
Chair, STCA Health Trust Fund
Bagpiper 2008 #1 Health Trust Newsletter
This and That
What a year the Trust has had, due to the kindness of so many people who have given so unselfishly to the programs we pursue. It is not possible here to name each of you; but the reader is encouraged to read the separate reports on donations appearing in each issue and to thank the clubs and individuals you know for their support.
I have been thinking for some time about some topics that I think you would like to know more about, and have chosen these ideas as the subject of this communication.
First, I want to thank the Board of the STCA for their thoughtfulness and foresight in returning Trustees Helen Prince and Pam Hendrickson for three- year terms to the Trust. In addition, and for the first time, the Trust has the services of a Certified Public Accountant! Lisa Kincheloe joined the Trust this fall to serve the third year of Kathi Brown’s term. Kathi has so many obligations that she had to leave us after two years of splendid service and contributions that saw numerous refinements to our Treasurer’s job, as well as her wise counsel on many matters the Trust considered during her term. We wish her the very best and thank her for her contributions.
I also want to take a moment to offer the reader insight into the process the Trust uses to insure that your donations are expended in the wisest possible manner. As many of you know, the Trust expends the bulk of our resources for research projects aimed at improving the health and well being of our dogs. We are aided in this effort by an alliance with the AKC Canine Health Foundation. The CHF matches and sometimes actually grants more than fifty percent of the cost of a proposed research project. In addition, CHF periodically surveys the breed club health arms, in order the assist them in the selection of grants relevant to the breeds, and to allow them to network multiple clubs with similar interests in a given problem. They then seek researchers with an interest in a problem and ask them to consider research proposals. Once a proposal is in their hands, they send the proposals to their expert panels for peer review of the scientific merit of a given proposal. Once the proposal has passed scientific scrutiny, it is submitted in the late fall to the breed health arms with a request for support.
Early on, the Health Trust concluded that the one to three paragraph abstracts we received from CHF offered insufficient information for us to make an informed judgment decision on the merit of the proposals. We approached CHF and requested that they submit the entire proposals to the Trust for consideration. Initially this caused considerable head-scratching at CHF, as they had not dealt with a request for this detail. They did in fact comply with our request, and soon we had the twenty to seventy page proposals in our hands for each Trustee to consider. Understand that these reports are highly scientific and technical in nature. Also understand that the Trust has a range of talents at our disposal, to include the services of a practicing veterinarian and a highly published clinical scientist. The Trust critically reviews the proposals prior to meeting and reaching a decision on the funding of the various proposals. At the most recent round of our decision making, we had eight proposals offered to us, and opted to fund two.
There are several reasons why we pursue this detailed consideration prior to expending funds. We owe it to the donors and to the dogs to make the best possible use of the available funds. Quite a few of the studies concern problems to be studied in other breeds, but which are tangential to the Scottish Terrier. Certainly, given unlimited resources there might be some additional studies we might approve and fund. This is not the case, so we feel the duty to make judgments that we believe offer the greatest mileage for your dollars.
In addition, the Trust continues to make efforts to further registry initiatives, such as our micro-chipping clinics, subsidized DNA profiling, and incentives to regional clubs to further extend efforts to conduct CERF clinics at regional specialties.
I know that it is apparent that my pride is showing over the quality of the overall program we have undertaken, and over the uniformly high quality and talents of your Trustees. I believe you can be proud of what we accomplish, and what we plan for the coming year. The Trust is driven by your confidence and support. All of the Trustees welcome your input, advice and suggestions for the future. Share your concerns with them and partner with us as we strive for a better future for your dogs. We thank you all!
Louis A. Mitchell, M.D.
Chair, STCA Health Trust Fund
Bagpiper 2007 #4 Health Trust Newsletter
The Health Trust Trustees met at the Summerfield Suites in Plymouth Meeting, PA. on October 4, 2007. One of the subjects we reviewed was the recent progress reports from the Canine Health Foundation on the various research projects recently completed and in progress. It is the intention of the Trust to publish in a future Bagpiper a complete report to the membership on the status of the various projects and it is our hope that this will appear in the next issue.
What I can say here is that the liver study by Dr. Zimmerman has concluded with interesting findings. His team looked at groups of dogs with both normal and elevated liver enzymes. They studied these two groups intensively to include liver biopsies. What they found was that the dogs with elevated liver enzymes appeared to have different and unusual adrenal cortical hormones not present in the dogs with normal liver enzymes. This led to a discussion of how we might use this information to help the owner. In the coming months we will be working on a survey that we want to enlist your help with. It was our feeling that if we could obtain large numbers of lab values correlated by age and other findings, we could develop better data on what is normally seen in the Scottish Terrier. This has been a vexing problem for all of us as we look at an elevated liver value and contemplate its meaning. This will be a long term project that could easily span years in terms of data collection. It is our hope that Dr. Zimmerman may be able to help us in terms of developing the survey that will be offered to you for your input.
Another report concerned the search for linkage to the gene responsible for CMO. Dr. Venta reported that he has searched three chromosomes nearly completely without finding the responsible gene. It is his intention to continue to search for the gene independent of Trust support and to again apply for research funding should he reach the point where it is needed. As many of you know, this has been a long term project and we intend to convey to Dr. Venta that we remain committed to resolution of this problem.
We reviewed all of the other projects which will be reported on soon. What is always needed in terms of the projects specific to the Scottish Terrier is additional samples from suitable dogs. In our breed, this presently includes blood from dogs diagnosed with cerebellar abiotrophy and their families, and blood from both dogs with transitional cell cancer of the bladder and normal dogs greater than five years of age who are not afflicted with this disease. The more samples we can offer to our researchers, the greater precision and power they have as they search for solutions to these problems.
We also discussed the Health Trust sponsored presentation to occur over the Rotating weekend in the Spring. Dr. Claudia Orlandi will join us for a presentation on anatomy and structure and the role they play in breeding the healthy dog. This will be in conjunction with the presentation by Mr. Jerry Roszman for both breeders and judges. Please make your plans to join us for this worthwhile and informative presentation by these two wonderful speakers.
On Friday, at LuLuTemple, the Trustees were on hand to provide assistance with the registry initiatives we began two years ago. As Helen judged the sweepstakes, we collected monies for 43 VetGen vWD test kits at the reduced price the Trust is able to offer at Montgomery and at Rotating. We also distributed 71 AKC DNA profile kits. These were sold at $20.00 each. AKC normally charges $40.00 for these kits, but they are available at national specialty shows for $30.00. The Trust subsidizes this test at ten dollars a test in order to be able to offer them to the public for $20.00. Additionally, we provided many dogs permanent microchipping and free patellar examinations in an effort to facilitate the registry initiatives. These examinations were provided by Trustee Dr. Pam Hendrickson, and Trustee Gail Gaines and Trustee Louis Mitchell completed the paperwork involved over about a two and a half hour period.
The Trust is joined by a new Trustee for the coming year. Lisa Kincheloe was elected by the Board of the STCA to fill the remaining term of Kathi Brown, who will be leaving the Trust after a remarkable two years. Kathi did a very great deal to enhance the Trust both with her wise counsel and her fine job as Treasurer. Lisa was elected Treasurer for the coming year. Lisa is a certified public accountant, in addition to having Scotties for many years, and we are indeed fortunate that she is joining us. Future donations to the Trust should be mailed to Lisa at:
22 Santa Lucia Ave.
Salinas, CA. 93901
The Trust is indeed fortunate to have the talents of a remarkable group of committed Trustees. Joanne Kinnelly has served the Trust and the STCA in nearly every office and capacity over many years. Joanne has bred quality dogs for many years. She brings great talent and experience to us. Gail Gaines has bred dogs for over forty years, operated the Scottiefile for the STCA, and brings great wisdom to the table. Helen Prince has similarly bred dogs for many, many years, and brings encyclopedic wisdom of the registry initiatives we pursue. Helen returns for a second three year term and will remain as Secretary to the Trust. Both Helen and Gail have also served the STCA in many capacities over many years. Dr. Pam Hendrickson is a veterinarian in private practice and has also returned for a second three year term on the Trust. Her background has been of tremendous help to the Trust over the past three years. Helen and Pam are the backbone of our Health Trust Newsletter sent to the regional clubs. Dr. John Leith is an extraordinary man whose wisdom and judgment we continue to exploit as we look at future endeavors for the Trust.
The Trust is deeply grateful to everyone who has given of their time and talents and money to make the Trust what it is today. There are so many who have given in so many ways that it is not possible to thank each of you by name. We thank you all.